(European) Valerian (Valeriana officinalis L.) is a perennial herbaceous plant belonging to the
honeysuckle family (Caprifoliaceae), native to Europe and Western Asia. Its roots are used
medicinally.

Historical Use:
As early as the 2nd century AD, valerian was documented in Europe for treating insomnia and
pain relief. By the 16th century, it was widely recognized as a sedative, anticonvulsant, and
herbal remedy for migraines.
Modern Research:
Scientific research on valerian began in the 1970s. In 1985, Germany’s Commission E
endorsed valerian as a sleep aid.

Distribution:
European Valerian (Valeriana officinalis L.): Predominantly found in Europe and Western
Asia.
East Asian Valerian (e.g., Valeriana coreana Brig.): Native to China and East Asia.
Active Compounds:
Western scholars generally identify valepotriates and valerenic acids as valerian’s primary
active constituents. Valerenic acids are often used as a quality standard for valerian and its
extracts. However, HPLC analysis reveals that valerenic acids are present in extremely low
levels in most non-European valerian species.
Evidence-Based Findings:
Insomnia: Multiple double-blind studies confirm that oral intake of 300–600 mg valerian
extract before bedtime facilitates faster sleep onset and improves sleep quality,
demonstrating efficacy for mild-to-moderate insomnia.
Anxiety: Double-blind studies indicate that combining valerian extract (100–200 mg/day,
3 times daily) with passionflower (Passiflora incarnata, 45–90 mg) effectively alleviates
anxiety symptoms, including anxiety-induced asthma, hysteria, and hypochondria.
Pain Relief: Historically used for its sedative and analgesic properties, though further
modern clinical studies are lacking.
Reference:
Huang Renquan, Zhang Li, Yang Jianli. "HPLC Analysis and Comparison of Valepotriates
and Valerenic Acids in Different Valerian Species." Chinese Traditional and Herbal Drugs,
2002, (11): 1000-1001.